Merz Aesthetics Radiesse fillers work in an instant to lift and improve contours. Radiesse fillers deliver a triple effect- Vertical lifting, Sharpened COntouir, and Neocollogenesis. Radiesse injections provide skin tightening, and beautify skiing by lifting, contouring, and defining the face and ensure long-term improvement. Merz Aesthetics Radiesse fillers are bio stimulators formulated with calcium hydroxylapatite microspheres that create new collagen.